Sr. Associate Scientist (Analytical Development/Gene Therapy) – Contract to Start/Top $$

Job Type: 
Life Sciences
Other Life Science Positions
Employment Category: 
Contract

Our client, a rapidly-expanding biopharma that is developing cutting edge therapies for the treatment of rare genetic diseases and cancers with a strong genetic component, is actively recruiting for a highly motivated and skilled scientist to join its CMC Analytical Development team.

This role will focus on testing the biophysical, structural and molecular attributes of rAAV-based gene therapy candidates.  This is an important role and company will pay excellent wage to attract and retain the right person.  

Key Things to Note:

  • This is a Palo Alto-based company with expanding operations in the RTP area.  This position will be on-site at its Raleigh lab. Significant safety/COVID precautions are employed.
  • This position will begin as a 6-8 month contract, with expectation of extension (and potential long-term opportunities) Ongoing expansion is planned.
  • Role will involve executing assay and testing activities of rAAV-based candidates to enable their cGMP production and release. Familiarity with techniques including LC, CE, q/ddPCR, ELISA, SDS-PAGE, H/UPLC, MS will be important.
  • This company is pursuing therapies for a wide range of life-altering conditions.  There is a (very) strong patient-focus and we seek candidates who are driven to find solutions.  
  • This is an emerging environment with a pitch-in-where-you-can culture.  Seek flexible and versatile candidate who enjoys a collaborative, high energy, low drama setting.

The Senior Associate Scientist will be a member of the CMC Analytical team and will work in partnership with the Non-Clinical Development, Upstream/Downstream Process/Formulation Development functions and external CROs to deliver products for clinical testing. 

Selected Responsibilities:

  • Run analytical assays such as ddPCR, ELISA, LC and CE in support non-clinical, CMC and clinical development of gene therapy drug candidates 
  • Perform the testing of routine samples and maintain rapid turnaround times
  • Document experimental data, results, and conclusions in an electronic laboratory notebook
  • May contribute to method development and SOP writing

Targeted candidate will offer a BS or MS in related science and 2+ years of lab experience in biotechnology and/or the biopharmaceutical field.  

Other priorities include:

  • Experience with most of the following assays: LC-MS, q/ddPCR, ELISA, Gel Electrophoresis (CE and cIEF), SDS-PAGE, H/UPLC,
  • Disciplined scientific documentation skills to support the writing of electronic notebook entries, SOPs, protocols and technical reports for internal documents and regulatory filings
  • Strong quality orientation
  • Unwavering commitment to the patient
  • Excellent written and verbal communication skills

Finally, we seek an intellectually-curious team player who is professional, focused, level-headed, reliable and eager to contribute to the shared goals. There is a lot happening and priorities shift daily.  We seek a self-motivated and get-things-done candidate who will thrive.

This is an immediate need.  Please forward Word resume for prompt consideration. Local candidates only.